OpenFold is a non-profit consortium building free, open-source AI tools for structural biology and drug discovery, trained, auditable, and available to everyone.

40+
Consortium Members
Apache 2.0
Permissively Licensed
OpenFold3
Now Available
Latest News

What's happening at OpenFold

BusinessWire

OpenFold Consortium Adds Eleven New Members

The consortium welcomed eleven new members, reflecting growing industry momentum behind open AI infrastructure for biology and drug discovery.

BusinessWire

Rocklin Lab Releases Megascale Open Protein Stability Dataset

The Rocklin Lab released a megascale open dataset of protein stability measurements to accelerate biomolecular AI research.

BusinessWire

OpenFold Launches Research Fellowship at UW Institute for Protein Design

OpenFold and UW's Institute for Protein Design launched a research fellowship to advance open-source AI for protein structure prediction and design.

Community Event

CoFold Summit

The annual gathering of the open biomolecular AI community.

Blind Challenge

SEPIQ Blind Challenge

A community blind challenge for structure-enabled property and interaction quantification.

Our Members

40+ organizations advancing open biomolecular AI

How to Contribute

Join the mission

OpenFold is built by a community that believes core structural-biology infrastructure should be open, reproducible, and extensible. Choose the contribution path that fits you best.

Join the Consortium

Consortium members contribute financially and/or technically and participate in community-driven roadmap decisions. Membership is primarily intended for organizations and is formalized through a participation agreement.

  • Influence high-impact roadmap priorities
  • Support open, retrainable modeling infrastructure
  • Connect with peer orgs on shared challenges

Collaborate

We welcome collaborations with researchers, academic labs, non-profits, and teams with aligned projects that improve rigor, usability, and real-world adoption.

  • Benchmarks, evaluations, and method development
  • Engineering support, pipelines, and integrations
  • Data and compute that strengthen reproducibility

Support via Philanthropy

OpenFold is hosted by the Open Molecular Software Foundation (OMSF), a 501(c)3 non-profit. Individuals, foundations, and Donor-Advised Funds can fund OMSF directly with OpenFold in the memo.

  • Find OMSF in DAF provider directories
  • Wire transfers accepted for philanthropic gifts
  • Email us for donation and routing details